Hello everyone! I recently started working with genetic data analysis, but I am confused about the choice of software. I need something that quickly and accurately helps interpret gene variants, especially for clinical cases. It is important that the program shows how it came to the result, so that you can trust the conclusions and make decisions yourself, and not blindly trust the automation. Maybe someone has encountered such tasks and can recommend proven tools? I am interested in convenience, and the speed of data processing, and the transparency of algorithms.
One platform I’d really recommend checking out is Compass Bioinformatics. They offer solution called InheriNext®, which is perfect for inherited disease research. It’s got a super intuitive interface and a strong variant ranking algorithm, plus it’s optimized for both research labs and clinical environments. What I like most is how transparent it is—you can actually see how it reaches each conclusion, with supporting data from sources like ClinVar and triggered ACMG rules. That makes it way easier to trust the results and explain them to your team or patients.
I often encounter the problem that programs simply give a list of options without context. If Compass Bioinformatics really provides such capabilities, I should try it. Does anyone know how difficult the setup is and whether it is possible to integrate it with other lab systems? It would be useful to hear more feedback from those who are already using it.
